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Female hormone Blood Testing

Our Female Hormone Blood Test can tell you whether a hormonal imbalance or thyroid problem may be causing your symptoms, such as acne, weight gain or tiredness. You can also uncover whether a hormonal imbalance may be affecting your fertility.

Measure your levels of female and thyroid hormones, which regulate fertility, mood, and energy.

Is it for me?

Our Female Hormone Blood Test can tell you whether a hormonal imbalance or thyroid problem may be causing your symptoms, such as acne, weight gain or tiredness. You can also uncover whether a hormonal imbalance may be affecting your fertility.

 

With our test, you can track your hormone levels and understand how they change over time. By monitoring your hormone levels, you can see whether your hormone levels are decreasing with age. If you take hormone replacement therapy (HRT), you can see if your hormone levels remain in the normal range.

What are female hormones?

Female hormones are essential for a healthy female reproductive system. Other functions of female hormones include fertility, mood, and energy. Oestradiol is the main female sex hormone, which is a type of oestrogen produced in the ovaries. Other essential female hormones include follicle-stimulating hormone (FSH), luteinising hormone (LH) and progesterone. Testosterone is a crucial hormone for women because your body uses it to make oestrogen. In women, hormone levels change naturally throughout the monthly menstrual cycle. Levels of oestrogen and progesterone can decrease with age, and women can experience a rise in FSH and LH levels during menopause.

What Are Symptoms Of A Hormonal Imbalance?

A hormonal imbalance can lead to unwanted symptoms such as acne, weight gain, mood changes, tiredness, and changes to your menstrual cycle. If your hormone levels are imbalanced for a long time, you could be at higher risk of health problems such as osteoporosis.

Why Do You Check My Thyroids?

Women are much more likely to experience a thyroid condition compared to men. A thyroid condition can cause similar symptoms to a hormonal imbalance, such as feeling tired or fatigued. This blood test also checks that your thyroid is functioning normally.

Limitation of the test?

If you are taking the test for fertility reasons, please take on day 2 or day 3 of your cycle. If taking the test for ovulation or progesterone levels please take on day 21 of your cycle (or 7 days before the next menstrual period is due, if longer than a 28-day cycle).

Biomarkers included?

Follicle Stimulating Hormone (FSH) is produced in the pituitary gland and is important for women in the production of eggs by the ovaries and for men for men in the production of sperm. In the first half of the menstrual cycle in women, FSH stimulates the enlargement of follicles within the ovaries. Each of these follicles will help to increase oestradiol levels. One follicle will become dominant and will be released by the ovary (ovulation), after which follicle stimulating hormone levels drop during the second half of the menstrual cycle. In men, FSH acts on the seminiferous tubules of the testicles where they stimulate immature sperm cells to develop into mature sperm.

 Luteinising Hormone (LH) is produced by the pituitary gland and is important for male and female fertility. In women it governs the menstrual cycle, peaking before ovulation. In men it stimulates the production of testosterone.

Oestradiol is a female steroid hormone, produced in the ovaries of women and to a much lesser extent in the testes of men. It is the strongest of three oestrogens and is responsible for the female reproductive system as well as the growth of breast tissue and bone thickness. In pre-menopausal women, oestradiol levels vary throughout the monthly cycle, peaking at ovulation. In women, oestradiol levels decline with age, culminating with the menopause when the ovaries stop producing eggs. Low oestradiol can cause many symptoms associated with the menopause, including hot flushes, night sweats and mood swings. Low oestradiol can also cause osteoporosis.

Testosterone is a hormone that causes male characteristics. For men, it helps to regulate sex drive and has a role in controlling bone mass, fat distribution, muscle mass, strength and the production of red blood cells and sperm. Testosterone is produced in the testicles of men and, in much smaller amounts, in the ovaries of women. Testosterone levels in men naturally decline after the age of 30, although lower than normal levels can occur at any age and can cause low libido, erectile dysfunction, difficulty in gaining and maintaining muscle mass and lack of energy. Although women have much lower amounts of testosterone than men, it is important for much the same reasons, playing a role in libido, the distribution of muscle and fat and the formation of red blood cells. All laboratories will slightly differ in the reference ranges they apply because they are based on the population they are testing. The normal range is set so that 95% of men will fall into it. For greater consistency, we use the guidance from the British Society for Sexual Medicine (BSSM) which advises that low testosterone can be diagnosed when testosterone is consistently below the reference range, and that levels below 12 nmol/L could also be considered low, especially in men who also report symptoms of low testosterone or who have low levels of free testosterone.

Most testosterone circulating in the blood is bound to proteins, in particular SHBG and albumin; only 2-3 % of testosterone is free and available to cells. This test uses an algorithm to calculate the level of free or unbound testosterone in relation to total testosterone, SHBG and albumin.

The Testosterone/Cortisol (T:C) ratio is a marker which shows promise in assessing whether athletes are recovering well after intense training. Testosterone is an anabolic hormone which helps to build muscle, produce red blood cells and increase aerobic metabolism in muscles. Cortisol is a catabolic hormone working antagonistically with testosterone, inhibiting protein synthesis and blocking anabolic signalling. The T:C ratio is more sensitive to the stresses of training than either measure alone. Over time it can be trended to see how well you are recovering.

Prolactin is a hormone which is produced in the pituitary gland and plays a role in reproductive health. Its primary purpose is to stimulate milk production after childbirth, and in pregnant and breastfeeding women prolactin levels can soar.

SHBG (sex hormone binding globulin) is a protein which transports the sex hormones (testosterone, oestrogen and dihydrotestosterone (DHT)) in the blood. Hormones which are bound to SHBG are inactive which means that they are unavailable to your cells. Measuring the level of SHBG in your blood gives important information about your levels of free or unbound hormones which are biologically active and available for use.

Thyroid stimulating hormone (TSH) is produced in the pituitary gland in order to regulate the production of thyroid hormones thyroxine (T4) and triiodothyronine (T3) by the thyroid gland. If thyroid hormones in the blood are low, then more TSH is produced to stimulate the thyroid gland to produce more of them. If thyroid hormone levels are high, then the pituitary produces less TSH to slow the production of thyroid hormones. If TSH is too high or too low, it normally signifies that there is a problem with the thyroid gland which is causing it to under or over produce thyroid hormones. Sometimes a disorder of the pituitary gland can also cause abnormal TSH levels.

Thyroxine (T4) is one of two hormones produced by the thyroid gland. It works to speed up the rate of your metabolism. Most T4 is bound to carrier proteins in the blood – it is only the free, or unbound, T4 that is active in the body, which is measured in this test. Free T4 is the less active of the two main thyroid hormones. To have an impact on your cells it needs to convert to the more active T3 when your body needs it.

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